Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis

The first enzyme of the shikimate pathway, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS), adopts a range of distinct allosteric regulation mechanisms in different organisms, related to different quaternary assemblies. DAH7PS from Mycobacterium tuberculosis (MtuDAH7PS) is a homotetram...

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Detalles Bibliográficos
Autores principales: Jiao, Wanting, Blackmore, Nicola J., Nazmi, Ali Reza, Parker, Emily J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493349/
https://www.ncbi.nlm.nih.gov/pubmed/28665948
http://dx.doi.org/10.1371/journal.pone.0180052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493349/
https://www.ncbi.nlm.nih.gov/pubmed/28665948
http://dx.doi.org/10.1371/journal.pone.0180052

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