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Regeneration of hyaline-like cartilage in situ with SOX9 stimulation of bone marrow-derived mesenchymal stem cells

Microfracture, a common procedure for treatment of cartilage injury, induces fibrocartilage repair by recruiting bone marrow derived mesenchymal stem cells (MSC) to the site of cartilage injury. However, fibrocartilage is inferior biomechanically to hyaline cartilage. SRY-type high-mobility group bo...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaowei, Wu, Shili, Naccarato, Ty, Prakash-Damani, Manan, Chou, Yuan, Chu, Cong-Qiu, Zhu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493350/
https://www.ncbi.nlm.nih.gov/pubmed/28666028
http://dx.doi.org/10.1371/journal.pone.0180138