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MicroRNA-148a overexpression improves the early development of porcine somatic cell nuclear transfer embryos

Incomplete epigenetic reprogramming of donor cell nuclei is one of the main contributors to the low efficiency of somatic cell nuclear transfer (SCNT). To improve the success of SCNT, somatic cell DNA methylation levels must be reduced to those levels found in totipotent embryonic cells. Recent stud...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Li, Xiangping, Cao, Lihua, Huang, Shihai, Li, Haiyan, Zhang, Yan, Yang, Ting, Jiang, Jianrong, Shi, Deshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493425/
https://www.ncbi.nlm.nih.gov/pubmed/28665977
http://dx.doi.org/10.1371/journal.pone.0180535