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MicroRNA-148a overexpression improves the early development of porcine somatic cell nuclear transfer embryos
Incomplete epigenetic reprogramming of donor cell nuclei is one of the main contributors to the low efficiency of somatic cell nuclear transfer (SCNT). To improve the success of SCNT, somatic cell DNA methylation levels must be reduced to those levels found in totipotent embryonic cells. Recent stud...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493425/ https://www.ncbi.nlm.nih.gov/pubmed/28665977 http://dx.doi.org/10.1371/journal.pone.0180535 |