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The role of PD-1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani

Programmed death-1 receptor (PD-1) expressed in many immune cells is known to trigger T-cell exhaustion but the significance of macrophage-associated PD-1 in relevance to macrophage apoptosis is not known. This study is aimed to delineate whether PD-1 pathway has any role in eliciting macrophage apo...

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Detalles Bibliográficos
Autores principales: Roy, Shalini, Gupta, Purnima, Palit, Shreyasi, Basu, Moumita, Ukil, Anindita, Das, Pijush K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493582/
https://www.ncbi.nlm.nih.gov/pubmed/28690843
http://dx.doi.org/10.1038/cti.2017.12