Inhibitors Alter the Stochasticity of Regulatory Proteins to Force Cells to Switch to the Other State in the Bistable System

The cellular behaviors under the control of genetic circuits are subject to stochastic fluctuations, or noise. The stochasticity in gene regulation, far from a nuisance, has been gradually appreciated for its unusual function in cellular activities. In this work, with Chemical Master Equation (CME),...

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Detalles Bibliográficos
Autores principales: Jhang, Wun-Sin, Lo, Shih-Chiang, Yeh, Chen-Chao, Shu, Che-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493615/
https://www.ncbi.nlm.nih.gov/pubmed/28667253
http://dx.doi.org/10.1038/s41598-017-04596-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493615/
https://www.ncbi.nlm.nih.gov/pubmed/28667253
http://dx.doi.org/10.1038/s41598-017-04596-7

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