Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time

Accumulation of progerin is believed to underlie the pathophysiology of Hutchinson-Gilford progeria syndrome, a disease characterized by clinical features suggestive of premature aging, including loss of subcutaneous white adipose tissue (sWAT). Although progerin has been found in cells and tissues...

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Detalles Bibliográficos
Autores principales: Revêchon, Gwladys, Viceconte, Nikenza, McKenna, Tomás, Sola Carvajal, Agustín, Vrtačnik, Peter, Stenvinkel, Peter, Lundgren, Torbjörn, Hultenby, Kjell, Franco, Irene, Eriksson, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493617/
https://www.ncbi.nlm.nih.gov/pubmed/28667315
http://dx.doi.org/10.1038/s41598-017-04492-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493617/
https://www.ncbi.nlm.nih.gov/pubmed/28667315
http://dx.doi.org/10.1038/s41598-017-04492-0

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