Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (GTKO.hCD4...

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Detalles Bibliográficos
Autores principales: Bongoni, Anjan K., Salvaris, Evelyn, Nordling, Sofia, Klymiuk, Nikolai, Wolf, Eckhard, Ayares, David L., Rieben, Robert, Magnusson, Peetra U., Cowan, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493627/
https://www.ncbi.nlm.nih.gov/pubmed/28667310
http://dx.doi.org/10.1038/s41598-017-04898-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493627/
https://www.ncbi.nlm.nih.gov/pubmed/28667310
http://dx.doi.org/10.1038/s41598-017-04898-w

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