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Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood
Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (GTKO.hCD4...
Autores principales: | Bongoni, Anjan K., Salvaris, Evelyn, Nordling, Sofia, Klymiuk, Nikolai, Wolf, Eckhard, Ayares, David L., Rieben, Robert, Magnusson, Peetra U., Cowan, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493627/ https://www.ncbi.nlm.nih.gov/pubmed/28667310 http://dx.doi.org/10.1038/s41598-017-04898-w |
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