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Post-secretional activation of Protease IV by quorum sensing in Pseudomonas aeruginosa

Protease IV (PIV), a key virulence factor of Pseudomonas aeruginosa is a secreted lysyl-endopeptidase whose expression is induced by quorum sensing (QS). We found that PIV expressed in QS mutant has severe reduction of activity in culture supernatant (CS), even though it is overexpressed to high lev...

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Detalles Bibliográficos
Autores principales: Oh, Jungmin, Li, Xi-Hui, Kim, Soo-Kyong, Lee, Joon-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493658/
https://www.ncbi.nlm.nih.gov/pubmed/28667333
http://dx.doi.org/10.1038/s41598-017-03733-6