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Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging

The dream of slowing down the aging process has always inspired mankind. Since stem cells are responsible for tissue and organ rejuvenation, it is logical that we should search for encoded mechanisms affecting life span in these cells. However, in adult life the hierarchy within the stem cell compar...

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Detalles Bibliográficos
Autores principales: Ratajczak, Mariusz Z., Bartke, Andrzej, Darzynkiewicz, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493720/
https://www.ncbi.nlm.nih.gov/pubmed/28229284
http://dx.doi.org/10.1007/s12015-017-9728-2