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Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging
The dream of slowing down the aging process has always inspired mankind. Since stem cells are responsible for tissue and organ rejuvenation, it is logical that we should search for encoded mechanisms affecting life span in these cells. However, in adult life the hierarchy within the stem cell compar...
Autores principales: | Ratajczak, Mariusz Z., Bartke, Andrzej, Darzynkiewicz, Zbigniew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493720/ https://www.ncbi.nlm.nih.gov/pubmed/28229284 http://dx.doi.org/10.1007/s12015-017-9728-2 |
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