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Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours

BACKGROUND: Natural killer (NK) cells play a critical role in cancer immunosurveillance. Recent developments in NK cell ex-vivo expansion makes it possible to generate millions of activated NK cells from a small volume of peripheral blood. We tested the functionality of ex vivo expanded NK cells in...

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Detalles Bibliográficos
Autores principales: Shenouda, Mira M., Gillgrass, Amy, Nham, Tina, Hogg, Richard, Lee, Amanda J., Chew, Marianne V., Shafaei, Mahsa, Aarts, Craig, Lee, Dean A., Hassell, John, Bane, Anita, Dhesy-Thind, Sukhbinder, Ashkar, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493877/
https://www.ncbi.nlm.nih.gov/pubmed/28668076
http://dx.doi.org/10.1186/s13058-017-0867-9