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Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours
BACKGROUND: Natural killer (NK) cells play a critical role in cancer immunosurveillance. Recent developments in NK cell ex-vivo expansion makes it possible to generate millions of activated NK cells from a small volume of peripheral blood. We tested the functionality of ex vivo expanded NK cells in...
Autores principales: | Shenouda, Mira M., Gillgrass, Amy, Nham, Tina, Hogg, Richard, Lee, Amanda J., Chew, Marianne V., Shafaei, Mahsa, Aarts, Craig, Lee, Dean A., Hassell, John, Bane, Anita, Dhesy-Thind, Sukhbinder, Ashkar, Ali A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493877/ https://www.ncbi.nlm.nih.gov/pubmed/28668076 http://dx.doi.org/10.1186/s13058-017-0867-9 |
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