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Splicing of human immunodeficiency virus RNA is position-dependent suggesting sequential removal of introns from the 5′ end

Transcription of the HIV-1 genome yields a single primary transcript, which is alternatively spliced to >30 mRNAs. Productive infection depends on inefficient and regulated splicing and appears to proceed in a tight 5′ to 3′ order. To analyse whether sequential splicing is mediated by the quality...

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Detalles Bibliográficos
Autores principales: Bohne, Jens, Wodrich, Harald, Kräusslich, Hans-Georg
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549389/
https://www.ncbi.nlm.nih.gov/pubmed/15701754
http://dx.doi.org/10.1093/nar/gki185