Catalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysis

Escherichia coli ribonuclease III (RNase III; EC 3.1.24) is a double-stranded(ds)-RNA-specific endonuclease with key roles in diverse RNA maturation and decay pathways. E.coli RNase III is a member of a structurally distinct superfamily that includes Dicer, a central enzyme in the mechanism of RNA i...

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Detalles Bibliográficos
Autores principales: Sun, Weimei, Pertzev, Alexandre, Nicholson, Allen W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549391/
https://www.ncbi.nlm.nih.gov/pubmed/15699182
http://dx.doi.org/10.1093/nar/gki197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549391/
https://www.ncbi.nlm.nih.gov/pubmed/15699182
http://dx.doi.org/10.1093/nar/gki197

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