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A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

Long interspersed nuclear elements (LINE-1 or L1) comprise 17% of the human genome, although only 80–100 L1s are considered retrotransposition-competent (RC-L1). Despite their small number, RC-L1s are still potential hazards to genome integrity through insertional mutagenesis, unequal recombination...

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Detalles Bibliográficos
Autores principales: Soifer, Harris S., Zaragoza, Adriana, Peyvan, Maany, Behlke, Mark A., Rossi, John J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549394/
https://www.ncbi.nlm.nih.gov/pubmed/15701756
http://dx.doi.org/10.1093/nar/gki223