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Sam68 is absolutely required for Rev function and HIV-1 production

Sam68 functionally complements for, as well as synergizes with, HIV-1 Rev in Rev response element (RRE)-mediated gene expression and virus production. Furthermore, C-terminal deletion/point mutants of Sam68 (Sam68ΔC/Sam68-P21) exert a transdominant negative phenotype for Rev function and HIV-1 produ...

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Detalles Bibliográficos
Autores principales: Modem, Suhasini, Badri, Kameswara R., Holland, Thomas C., Reddy, Thipparthi R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549398/
https://www.ncbi.nlm.nih.gov/pubmed/15701759
http://dx.doi.org/10.1093/nar/gki231