Molecular recognition of DNA base pairs by the formamido/pyrrole and formamido/imidazole pairings in stacked polyamides

Polyamides containing an N-terminal formamido (f) group bind to the minor groove of DNA as staggered, antiparallel dimers in a sequence-specific manner. The formamido group increases the affinity and binding site size, and it promotes the molecules to stack in a staggered fashion thereby pairing its...

Descripción completa

Detalles Bibliográficos
Autores principales: Buchmueller, Karen L., Staples, Andrew M., Uthe, Peter B., Howard, Cameron M., Pacheco, Kimberly A. O., Cox, Kari K., Henry, James A., Bailey, Suzanna L., Horick, Sarah M., Nguyen, Binh, Wilson, W. David, Lee, Moses
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549405/
https://www.ncbi.nlm.nih.gov/pubmed/15703305
http://dx.doi.org/10.1093/nar/gki238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549405/
https://www.ncbi.nlm.nih.gov/pubmed/15703305
http://dx.doi.org/10.1093/nar/gki238

Ejemplares similares