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P-Rex1 Expression in Invasive Breast Cancer in relation to Receptor Status and Distant Metastatic Site

BACKGROUND: Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (P-Rex1) has been implicated in cancer growth, metastasis, and response to phosphatidylinositol 3-kinase (PI3K) inhibitor therapy. The aim of this study was to determine whether P-Rex1 expression differs between pri...

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Detalles Bibliográficos
Autores principales: Marotti, Jonathan D., Muller, Kristen E., Tafe, Laura J., Demidenko, Eugene, Miller, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494073/
https://www.ncbi.nlm.nih.gov/pubmed/28698809
http://dx.doi.org/10.1155/2017/4537532