Cargando…

Amplification and propagation of interleukin-1β signaling by murine brain endothelial and glial cells

BACKGROUND: During acute infections and chronic illnesses, the pro-inflammatory cytokine interleukin-1β (IL-1β) acts within the brain to elicit metabolic derangements and sickness behaviors. It is unknown which cells in the brain are the proximal targets for IL-1β with respect to the generation of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Krasnow, Stephanie M., Knoll, J. Gabriel, Verghese, Santhosh Chakkaramakkil, Levasseur, Peter R., Marks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494131/
https://www.ncbi.nlm.nih.gov/pubmed/28668091
http://dx.doi.org/10.1186/s12974-017-0908-4