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Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex

BACKGROUND: Histone deacetylase 6 (HDAC6) is a microtubule-associated deacetylase that promotes many cellular processes that lead to cell transformation and tumour development. We previously documented an interaction between Ran-Binding Protein M (RanBPM) and HDAC6 and found that RanBPM expression i...

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Detalles Bibliográficos
Autores principales: Salemi, Louisa M., Maitland, Matthew E. R., Yefet, Eyal R., Schild-Poulter, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494137/
https://www.ncbi.nlm.nih.gov/pubmed/28668087
http://dx.doi.org/10.1186/s12885-017-3430-2