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Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex
BACKGROUND: Histone deacetylase 6 (HDAC6) is a microtubule-associated deacetylase that promotes many cellular processes that lead to cell transformation and tumour development. We previously documented an interaction between Ran-Binding Protein M (RanBPM) and HDAC6 and found that RanBPM expression i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494137/ https://www.ncbi.nlm.nih.gov/pubmed/28668087 http://dx.doi.org/10.1186/s12885-017-3430-2 |