Mutant p53 proteins bind DNA in a DNA structure-selective mode

Despite the loss of sequence-specific DNA binding, mutant p53 (mutp53) proteins can induce or repress transcription of mutp53-specific target genes. To date, the molecular basis for transcriptional modulation by mutp53 is not understood, but increasing evidence points to the possibility that specifi...

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Detalles Bibliográficos
Autores principales: Göhler, Thomas, Jäger, Stefan, Warnecke, Gabriele, Yasuda, Hideyo, Kim, Ella, Deppert, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549414/
https://www.ncbi.nlm.nih.gov/pubmed/15722483
http://dx.doi.org/10.1093/nar/gki252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549414/
https://www.ncbi.nlm.nih.gov/pubmed/15722483
http://dx.doi.org/10.1093/nar/gki252

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