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Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

BACKGROUND: Daptomycin is a recently introduced, last-resort antibiotic that displays a unique mode of action against Gram-positive bacteria that is not fully understood. Several bacterial targets have been proposed but no human binding partner is known. METHODS: In the present study we tested dapto...

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Detalles Bibliográficos
Autores principales: Gotsbacher, Michael P., Cho, Sungmin, Kwon, Ho Jeong, Karuso, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494143/
https://www.ncbi.nlm.nih.gov/pubmed/28680364
http://dx.doi.org/10.1186/s12953-017-0124-2