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CCR7 and CXCR4 Expression in Primary Head and Neck Squamous Cell Carcinomas and Nodal Metastases – a Clinical and Immunohistochemical Study

BACKGROUND: Squamous cell carcinomas (SCCs) are common head and neck malignancies demonstrating lymph node LN involvement. Recently chemokine receptor overxpression has been reported in many cancers. Of particular interest, CCR7 appears to be a strong mediator of LN metastases, while CXCR4 may media...

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Detalles Bibliográficos
Autores principales: Al-Jokhadar, Maya, Al-Mandily, Ahmad, Zaid, Khaled, Maalouf, Elie Azar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494221/
https://www.ncbi.nlm.nih.gov/pubmed/28547946
http://dx.doi.org/10.22034/APJCP.2017.18.4.1093