Enterolactone Suppresses Proliferation, Migration and Metastasis of MDA-MB-231 Breast Cancer Cells Through Inhibition of uPA Induced Plasmin Activation and MMPs-Mediated ECM Remodeling

BACKGROUND: To enhance their own survival, tumor cells can manipulate their microenvironment through remodeling of the extra cellular matrix (ECM). The urokinase-type plasminogen activator (uPA) system catalyzes plasmin production which further mediates activation of matrix metalloproteinases (MMPs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Mali, Aniket V, Joshi, Asavari A, Hegde, Mahabaleshwar V, Kadam, Shivajirao S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494239/
https://www.ncbi.nlm.nih.gov/pubmed/28545187
http://dx.doi.org/10.22034/APJCP.2017.18.4.905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494239/
https://www.ncbi.nlm.nih.gov/pubmed/28545187
http://dx.doi.org/10.22034/APJCP.2017.18.4.905

Ejemplares similares