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Enterolactone Suppresses Proliferation, Migration and Metastasis of MDA-MB-231 Breast Cancer Cells Through Inhibition of uPA Induced Plasmin Activation and MMPs-Mediated ECM Remodeling

BACKGROUND: To enhance their own survival, tumor cells can manipulate their microenvironment through remodeling of the extra cellular matrix (ECM). The urokinase-type plasminogen activator (uPA) system catalyzes plasmin production which further mediates activation of matrix metalloproteinases (MMPs)...

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Detalles Bibliográficos
Autores principales:	Mali, Aniket V, Joshi, Asavari A, Hegde, Mahabaleshwar V, Kadam, Shivajirao S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494239/ https://www.ncbi.nlm.nih.gov/pubmed/28545187 http://dx.doi.org/10.22034/APJCP.2017.18.4.905

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