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Sequence motifs capable of forming DNA stem–loop structures act as a replication diode

Calculating peak‐height ratios between single‐nucleotide polymorphisms (SNP) alleles in sequencing chromatograms is a practical method for estimating their copy number proportions (CNPs). However, it is surprising that sequencing DNA from different directions might yield different results. We analyz...

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Detalles Bibliográficos
Autores principales: Shirak, Andrey, Seroussi, Uri, Gootwine, Elisha, Seroussi, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494291/
https://www.ncbi.nlm.nih.gov/pubmed/28680808
http://dx.doi.org/10.1002/2211-5463.12233