Sulforaphane-cysteine-induced apoptosis via phosphorylated ERK1/2-mediated maspin pathway in human non-small cell lung cancer cells

Sulforaphane (SFN) was demonstrated to induce apoptosis in a variety of cancers via multiple mechanisms. However, owing to a short half-life in circulation, SFN was not used for clinical treatment yet. Interestingly, SFN analog, sulforaphane-cysteine (SFN-Cys) has a longer half-life in metabolism, a...

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Detalles Bibliográficos
Autores principales: Lin, Kai, Yang, Ronghui, Zheng, Zhongnan, Zhou, Yan, Geng, Yang, Hu, Yabin, Wu, Sai, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494314/
https://www.ncbi.nlm.nih.gov/pubmed/28690874
http://dx.doi.org/10.1038/cddiscovery.2017.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494314/
https://www.ncbi.nlm.nih.gov/pubmed/28690874
http://dx.doi.org/10.1038/cddiscovery.2017.25

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