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Recognition of the spliceosomal branch site RNA helix on the basis of surface and electrostatic features
We have investigated electrostatic and surface features of an essential region of the catalytic core of the spliceosome, the eukaryotic precursor messenger (pre-m)RNA splicing apparatus. The nucleophile for the first of two splicing reactions is the 2′-hydroxyl (OH) of the ribose of a specific adeno...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549433/ https://www.ncbi.nlm.nih.gov/pubmed/15728744 http://dx.doi.org/10.1093/nar/gki249 |