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Secondary biopsy of non‐oncogenic‐driven lung cancer may reveal a clinically sensible histologic change. A brief report of two paradigmatic cases

After an initial benefit, non‐small‐cell lung cancer (NSCLC) patients receiving therapy with tyrosine kinase inhibitors develop drug resistance through a variety of mechanisms. Among these, tumor histology changes are a mechanism of acquired resistance in epidermal growth factor receptor‐mutated and...

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Detalles Bibliográficos
Autores principales: Mengoli, Maria C., Orsi, Giulia, Lococo, Filippo, Grizzi, Giulia, Barbieri, Fausto, Bertolini, Federica, Rossi, Giulio, Novello, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494451/
https://www.ncbi.nlm.nih.gov/pubmed/28383810
http://dx.doi.org/10.1111/1759-7714.12416