A genome editing approach to study cancer stem cells in human tumors

The analysis of stem cell hierarchies in human cancers has been hampered by the impossibility of identifying or tracking tumor cell populations in an intact environment. To overcome this limitation, we devised a strategy based on editing the genomes of patient‐derived tumor organoids using CRISPR/Ca...

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Detalles Bibliográficos
Autores principales: Cortina, Carme, Turon, Gemma, Stork, Diana, Hernando‐Momblona, Xavier, Sevillano, Marta, Aguilera, Mònica, Tosi, Sébastien, Merlos‐Suárez, Anna, Stephan‐Otto Attolini, Camille, Sancho, Elena, Batlle, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494503/
https://www.ncbi.nlm.nih.gov/pubmed/28468934
http://dx.doi.org/10.15252/emmm.201707550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494503/
https://www.ncbi.nlm.nih.gov/pubmed/28468934
http://dx.doi.org/10.15252/emmm.201707550

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