Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

Hydrocephalus is a common congenital anomaly. LCAM1 and MPDZ (MUPP1) are the only known human gene loci associated with non‐syndromic hydrocephalus. To investigate functions of the tight junction‐associated protein Mpdz, we generated mouse models. Global Mpdz gene deletion or conditional inactivatio...

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Detalles Bibliográficos
Autores principales: Feldner, Anja, Adam, M Gordian, Tetzlaff, Fabian, Moll, Iris, Komljenovic, Dorde, Sahm, Felix, Bäuerle, Tobias, Ishikawa, Hiroshi, Schroten, Horst, Korff, Thomas, Hofmann, Ilse, Wolburg, Hartwig, von Deimling, Andreas, Fischer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494508/
https://www.ncbi.nlm.nih.gov/pubmed/28500065
http://dx.doi.org/10.15252/emmm.201606430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494508/
https://www.ncbi.nlm.nih.gov/pubmed/28500065
http://dx.doi.org/10.15252/emmm.201606430

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