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The Controversial C5a Receptor C5aR2: Its Role in Health and Disease

After the discovery of the C5a receptor C5aR1, C5aR2 is the second receptor found to bind C5a and its des-arginine form. As a heptahelical G protein-coupled receptor but devoid of the intracellular Gα signal, C5aR2 is special and confusing. Ramifications and controversies about C5aR2 are under debat...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Garstka, Malgorzata A., Li, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494583/
https://www.ncbi.nlm.nih.gov/pubmed/28706957
http://dx.doi.org/10.1155/2017/8193932