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Resistance to epithelial growth factor receptor tyrosine kinase inhibitors in a patient with transformation from lung adenocarcinoma to small cell lung cancer: A case report

First-generation epithelial growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have markedly improved the treatment of non-small cell lung cancer (non-SCLC) with EGFR-sensitive mutations. However, acquired resistance to these drugs was inevitable. The transformation of lung adenocarcinoma...

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Detalles Bibliográficos
Autores principales: Fang, Liying, He, Jian, Xia, Jingwen, Dong, Liang, Zhang, Xiujuan, Chai, Yaqin, Li, Ying, Niu, Mengjie, Hang, Tianxing, Li, Shengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494666/
https://www.ncbi.nlm.nih.gov/pubmed/28693210
http://dx.doi.org/10.3892/ol.2017.6229