Japanese apricot extract (MK615) potentiates bendamustine-induced apoptosis via impairment of the DNA damage response in lymphoma cells

Bendamustine, a hybrid molecule of a purine analog and alkylator, induces cell death by the activation of apoptosis and the DNA damage response. The agent MK615 is produced from Japanese apricot and contains a number of cyclic triterpenes that exhibit antitumor activities. In the present study, the...

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Detalles Bibliográficos
Autores principales: Inoue, Masaya, Honma, Yoshio, Urano, Takeshi, Suzumiya, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494765/
https://www.ncbi.nlm.nih.gov/pubmed/28693235
http://dx.doi.org/10.3892/ol.2017.6219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494765/
https://www.ncbi.nlm.nih.gov/pubmed/28693235
http://dx.doi.org/10.3892/ol.2017.6219

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