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Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions

Recent advances in the expansion and directed pancreatogenic differentiation of human pluripotent stem cells (hPSCs) have intensified efforts to generate functional pancreatic islet cells, especially insulin-secreting β-cells, for cell therapies against diabetes. However, the consistent generation o...

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Detalles Bibliográficos
Autores principales: Jacobson, Elena F., Tzanakakis, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494890/
https://www.ncbi.nlm.nih.gov/pubmed/28680477
http://dx.doi.org/10.1186/s13036-017-0066-3