Mechanisms of precise genome editing using oligonucleotide donors

The use of programmable meganucleases is transforming genome editing and functional genomics. CRISPR/Cas9 was developed such that targeted genomic lesions could be introduced in vivo with unprecedented ease. In the presence of homology donors, these lesions facilitate high-efficiency precise genome...

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Detalles Bibliográficos
Autores principales: Kan, Yinan, Ruis, Brian, Takasugi, Taylor, Hendrickson, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495063/
https://www.ncbi.nlm.nih.gov/pubmed/28356322
http://dx.doi.org/10.1101/gr.214775.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495063/
https://www.ncbi.nlm.nih.gov/pubmed/28356322
http://dx.doi.org/10.1101/gr.214775.116

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