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Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

RNA editing, a widespread post-transcriptional mechanism, has emerged as a new player in cancer biology. Recent studies have reported key roles for individual miRNA editing events, but a comprehensive picture of miRNA editing in human cancers remains largely unexplored. Here, we systematically chara...

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Detalles Bibliográficos
Autores principales: Wang, Yumeng, Xu, Xiaoyan, Yu, Shuangxing, Jeong, Kang Jin, Zhou, Zhicheng, Han, Leng, Tsang, Yiu Huen, Li, Jun, Chen, Hu, Mangala, Lingegowda S., Yuan, Yuan, Eterovic, A. Karina, Lu, Yiling, Sood, Anil K., Scott, Kenneth L., Mills, Gordon B., Liang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495064/
https://www.ncbi.nlm.nih.gov/pubmed/28411194
http://dx.doi.org/10.1101/gr.219741.116