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YY1 and CTCF orchestrate a 3D chromatin looping switch during early neural lineage commitment

CTCF is an architectural protein with a critical role in connecting higher-order chromatin folding in pluripotent stem cells. Recent reports have suggested that CTCF binding is more dynamic during development than previously appreciated. Here, we set out to understand the extent to which shifts in g...

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Detalles Bibliográficos
Autores principales: Beagan, Jonathan A., Duong, Michael T., Titus, Katelyn R., Zhou, Linda, Cao, Zhendong, Ma, Jingjing, Lachanski, Caroline V., Gillis, Daniel R., Phillips-Cremins, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495066/
https://www.ncbi.nlm.nih.gov/pubmed/28536180
http://dx.doi.org/10.1101/gr.215160.116