Cargando…

Accumulation of RNA on chromatin disrupts heterochromatic silencing

Long noncoding RNAs (lncRNAs) play a conserved role in regulating gene expression, chromatin dynamics, and cell differentiation. They serve as a platform for RNA interference (RNAi)–mediated heterochromatin formation or DNA methylation in many eukaryotic organisms. We found in Schizosaccharomyces po...

Descripción completa

Detalles Bibliográficos
Autores principales: Brönner, Cornelia, Salvi, Luca, Zocco, Manuel, Ugolini, Ilaria, Halic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495069/
https://www.ncbi.nlm.nih.gov/pubmed/28404620
http://dx.doi.org/10.1101/gr.216986.116