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Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha

Microbiota influence diverse aspects of intestinal physiology and disease in part by controlling tissue-specific transcription of host genes. However, host genomic mechanisms mediating microbial control of intestinal gene expression are poorly understood. Hepatocyte nuclear factor 4 (HNF4) is the mo...

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Detalles Bibliográficos
Autores principales: Davison, James M., Lickwar, Colin R., Song, Lingyun, Breton, Ghislain, Crawford, Gregory E., Rawls, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495071/
https://www.ncbi.nlm.nih.gov/pubmed/28385711
http://dx.doi.org/10.1101/gr.220111.116