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Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha
Microbiota influence diverse aspects of intestinal physiology and disease in part by controlling tissue-specific transcription of host genes. However, host genomic mechanisms mediating microbial control of intestinal gene expression are poorly understood. Hepatocyte nuclear factor 4 (HNF4) is the mo...
Autores principales: | Davison, James M., Lickwar, Colin R., Song, Lingyun, Breton, Ghislain, Crawford, Gregory E., Rawls, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495071/ https://www.ncbi.nlm.nih.gov/pubmed/28385711 http://dx.doi.org/10.1101/gr.220111.116 |
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