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Histone demethylase KDM2B upregulates histone methyltransferase EZH2 expression and contributes to the progression of ovarian cancer in vitro and in vivo

Aberrant histone methylation contributes to the progression and development of many tumors. Histone methylation is a dynamic process regulated by both histone demethylase and histone methyltransferase, which ultimately alters the levels of gene transcription. However, the relationship between histon...

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Detalles Bibliográficos
Autores principales: Kuang, Yan, Lu, Fangfang, Guo, Jianfeng, Xu, Hong, Wang, Qi, Xu, Chaohuan, Zeng, Longjia, Yi, Suyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495092/
https://www.ncbi.nlm.nih.gov/pubmed/28706445
http://dx.doi.org/10.2147/OTT.S134784