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Histone demethylase KDM2B upregulates histone methyltransferase EZH2 expression and contributes to the progression of ovarian cancer in vitro and in vivo
Aberrant histone methylation contributes to the progression and development of many tumors. Histone methylation is a dynamic process regulated by both histone demethylase and histone methyltransferase, which ultimately alters the levels of gene transcription. However, the relationship between histon...
Autores principales: | Kuang, Yan, Lu, Fangfang, Guo, Jianfeng, Xu, Hong, Wang, Qi, Xu, Chaohuan, Zeng, Longjia, Yi, Suyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495092/ https://www.ncbi.nlm.nih.gov/pubmed/28706445 http://dx.doi.org/10.2147/OTT.S134784 |
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