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Settling the m(6)A debate: methylation of mature mRNA is not dynamic but accelerates turnover
Post-transcriptional modification of RNA nucleosides has been implicated as a pivotal regulator of mRNA biology. In this issue of Genes & Development, Ke and colleagues (pp. 990–1006) provide insights into the temporal and spatial distribution of N(6)-methyladenosine (m(6)A) in RNA transcripts b...
Autores principales: | Rosa-Mercado, Nicolle A., Withers, Johanna B., Steitz, Joan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495124/ https://www.ncbi.nlm.nih.gov/pubmed/28637691 http://dx.doi.org/10.1101/gad.302695.117 |
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