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PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

Developmental and lineage plasticity have been observed in numerous malignancies and have been correlated with tumor progression and drug resistance. However, little is known about the molecular mechanisms that enable such plasticity to occur. Here, we describe the function of the plant homeodomain...

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Detalles Bibliográficos
Autores principales: Soto-Feliciano, Yadira M., Bartlebaugh, Jordan M.E., Liu, Yunpeng, Sánchez-Rivera, Francisco J., Bhutkar, Arjun, Weintraub, Abraham S., Buenrostro, Jason D., Cheng, Christine S., Regev, Aviv, Jacks, Tyler E., Young, Richard A., Hemann, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495126/
https://www.ncbi.nlm.nih.gov/pubmed/28607179
http://dx.doi.org/10.1101/gad.295857.117