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Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema

BACKGROUND: Apoptosis has recently been proposed to contribute to the pathogenesis of emphysema. METHODS: In order to establish if cell fate plays a role even in end-stage disease we studied 16 lungs (9 smoking-associated and 7 α1antitrypsin (AAT)-deficiency emphysema) from patients who had undergon...

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Detalles Bibliográficos
Autores principales: Calabrese, Fiorella, Giacometti, Cinzia, Beghe, Bianca, Rea, Federico, Loy, Monica, Zuin, Renzo, Marulli, Giuseppe, Baraldo, Simonetta, Saetta, Marina, Valente, Marialuisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549521/
https://www.ncbi.nlm.nih.gov/pubmed/15705190
http://dx.doi.org/10.1186/1465-9921-6-14