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FceRI density and spontaneous secretion from human basophils

Mast cells and basophils depend on aggregation of the high-affinity IgE receptor, FceRI, to initiate secretion. A variety of studies have shown that FceRI densities vary 100 fold among subjects’ basophils and it has been speculated that high densities might be responsible for unusual behaviors of th...

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Detalles Bibliográficos
Autor principal: MacGlashan, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495218/
https://www.ncbi.nlm.nih.gov/pubmed/28671980
http://dx.doi.org/10.1371/journal.pone.0179734