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Cardioprotective effects of PKG activation by soluble GC activator, BAY 60-2770, in ischemia-reperfusion-injured rat hearts

Soluble guanylate cyclase (sGC) has been suggested as a therapeutic target for cardiac ischemia-reperfusion (IR) injury. Until now, the molecular mechanism of BAY 60–2770, a sGC activator, in cardiac IR injury has not been assessed. To identify the cardioprotective effects of BAY 60–2770 in IR-injur...

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Detalles Bibliográficos
Autores principales: Lee, Kyung Hye, Lee, So-Ra, Cho, Haneul, Woo, Jong Shin, Kang, Jung Hee, Jeong, Yun-Mi, Cheng, Xian Wu, Kim, Woo-Shik, Kim, Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495340/
https://www.ncbi.nlm.nih.gov/pubmed/28671970
http://dx.doi.org/10.1371/journal.pone.0180207