Mass spectrometrical analysis of recombinant human growth hormone (Genotropin(®)) reveals amino acid substitutions in 2% of the expressed protein

BACKGROUND: The structural integrity of recombinant proteins is of critical importance to their application as clinical treatments. Recombinant growth hormone preparations have been examined by several methodologies. In this study recombinant human growth hormone (rhGH; Genotropin(®)), expressed in...

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Detalles Bibliográficos
Autores principales: Hepner, Felix, Cszasar, Edina, Roitinger, Elisabeth, Lubec, Gert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549540/
https://www.ncbi.nlm.nih.gov/pubmed/15707495
http://dx.doi.org/10.1186/1477-5956-3-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549540/
https://www.ncbi.nlm.nih.gov/pubmed/15707495
http://dx.doi.org/10.1186/1477-5956-3-1

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